6 Things to Know About Peptic Ulcer Disease

Bruce Springsteen postponed the remainder of his September concert performances as the 73-year-old singer gets treatment for symptoms of peptic ulcer disease. In a statement on his official website, the rock legend assured his fans that he’ll “be back soon.”

About 1 in 10 Americans will develop a peptic ulcer at some point in their lives, most commonly in middle age. The open sore or raw spot that forms in the lining of the stomach or small intestine can cause heartburn, nausea and stomach pain.

The good news for sufferers like Springsteen is that the prognosis for recovery from peptic ulcer disease is excellent after the underlying cause is successfully treated, according to the National Institutes of Health (NIH). It generally takes several weeks of treatment —which can range from an endoscopy procedure to prescription medications including antibiotics to protein pump inhibitors — for an ulcer to heal.

1. You may have an ulcer and not know it

Many older adults with an ulcer have few or no symptoms. And for adults who do have symptoms, they can vary. The most common symptoms are abdominal pain, heartburn and the sensation of acid backing up into the throat. Other symptoms can include bloating, a feeling of fullness, hunger and belching. Pain symptoms are often described as a burning or gnawing in the stomach.

Ulcers that form in the small intestine tend to cause more consistent pain, often appearing mid-morning and recurring about two to three hours after a meal. Pain from stomach ulcers often doesn’t follow a consistent pattern, according to the Merck Manual and the Icahn School of Medicine at Mount Sinai.

2. Stress isn’t behind the disease

Stress doesn’t cause peptic ulcers. However, it can make your symptoms worse, according to the Mayo Clinic. In most cases, peptic ulcers are caused by a bacterial infection from Helicobacter pylori that can sometimes cause inflammation of the stomach’s inner layer, producing an ulcer. The bacterium causes 90 percent of small intestine ulcers and 70 to 90 percent of stomach ulcers, according to the NIH.

The second most common cause of ulcers is long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs), which can lead to a decrease in the gastric mucus that helps protect the inner lining of the stomach and small intestine. Women and older adults seem to be more susceptible to this, according to Harvard Medical School.

3. Some are more at risk than others

Peptic ulcer disease can occur at any age, though it is rare in children. Men are more likely than women to develop the disease. The risk of an ulcer in the first segment of the small intestine, or duodenum, is greatest among those ages 55 to 65.